Historical mystery dramas can be a neat combination of genres, especially if they’re like The Apothecary Diaries. Based on Natsu Hyūga’s novel, it tells the story of Maomao, an apothecary taken from her home in the red-light district to serve the emperor. At first, she planned to keep to herself, but after learning the emperor’s children were critically ill, she examined them in secret and discovered why they were sick.


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This was only the start of her adventures, as Jinshi, an influential eunuch, pulls her into one case or another that requires her medicinal, botanical, and chemical knowledge. After gaining a light novel and manga adaptation, it made the leap to anime, with a series that’s still currently running on Crunchyroll as of this writing. But once it’s over, fans may like to check out these similar historical anime shows.


8 Snow White with the Red Hair

MyAnimeList Score: 7.76

Anime Like The Apothecary Diaries- Snow White With the Red Hair

  • Creator: Sorata Akizuki.
  • Studio: Bones.
  • 2 Seasons, 24 Episodes.
  • Available on Crunchyroll and Funimation.

The Apothecary Diaries is technically a fantasy series, but its fictional nation of Ri is based so heavily on Imperial China that it may as well be the old country. Snow White with the Red Hair has a more typical medieval European look to it, but it shares quite a few things in common with TAD. Namely, in how they’re both about forthright women who get caught up in royal drama.

Shirayuki grew up in the Kingdom of Tanbarun, where she set up shop as a herbalist. Though she catches the amorous attention of Prince Raj, she’d rather flee the country than become his concubine. She ends up taking residence in the nearby Kingdom of Clarines, where she saves Prince Zen after he’s poisoned. She becomes the court herbalist, where she helps others with her medical skills and finds love in the process.

7 Gosick

MyAnimeList Score: 8.05

gosick anime

  • Creator: Kazuki Sakuraba (writer), Hinata Takeda (illustrator).
  • Studio: Bones.
  • 1 Season, 24 Episodes.
  • Available on Crunchyroll and Funimation.

Compared to the other series on this list, Gosick (based on the Japanese pronunciation of ‘gothic’) practically takes place in the modern day. Set in 1924, Kazuya Kujō is sent from Japan to the fictional Alpine nation of Sauville to study at St Marguerite Academy. He’s treated with suspicion as, aside from racism, the school has a superstition that says, “the traveler that comes in spring brings death with him”.

The only ‘friend’ he makes is Victorique de Blois, an elegant beauty with a genius intellect, and an abrasive personality. He ends up as the unwitting Watson to her Sherlock Holmes as the two solve crimes together, where he often suffers from her barbed remarks. Nonetheless, the two gradually warm to each other as time goes on. Especially when Victorique’s past comes back to bite her.

6 Moriarty the Patriot

MyAnimeList Score: 8.17

Moriarty the Patriot Season 2

Moriarty the Patriot
Seasons
2

Number of Episodes
24

Creator
Ryōsuke Takeuchi

Studio
Production I.G

Speaking of Sherlock Holmes, Moriarty the Patriot essentially tells the classic detective stories from the perspective of its main villain. Kind of. Set during the late 19th century, it sees Albert Moriarty adopt two orphans as his brothers, and the trio plots to bring down the corrupt British nobility. The middle brother, William, is the most ambitious, coming up with elaborate schemes to create the perfect crimes.

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The only obstacle in his way is, of course, Sherlock Holmes. When he figures out one of William’s plots, William frames him for murder just to see how he’ll wriggle out of it. From there, the two end up forming an odd relationship where William tries to use Sherlock in his plans to reform society, while Sherlock would rather not be involved yet still sees William as a friend. In the show, Watson’s accounts become the classic Sherlock Holmes novels.

5 Emma: A Victorian Romance

MyAnimeList Score: 7.61

Anime Like The Apothecary Diaries- Emma A Victorian Romance

Emma: A Victorian Romance
Seasons
1

Number of Episodes
12

Creator
Kaoru Mori

Studio
Pierrot

Moriarty the Patriot has the historical setting and mystery elements of The Apothecary Diaries, though it has more bromance than romance. By contrast, and as its title suggests, Emma: A Victorian Romance has romance and history, but not really any mystery-solving. It makes up for that by being a surprisingly realistic take on 19th-century Britain and its social classes.

Emma was kidnapped from her Yorkshire village to serve in a London brothel, but she managed to escape. Left on the streets, she’s taken in by Mrs Stownar to become her maid in training. Things only get complicated when William, the heir to a rich middle-class family, falls for her rather than someone in his caste. With his family urging against them, but their friends supporting them, Emma and William’s love becomes a complicated affair.

4 Undead Murder Farce

MyAnimeList Score: 7.90

Anime Like The Apothecary Diaries- Undead Murder Farce

Undead Murder Farce
Seasons
1

Number of Episodes
13

Creator
Yugo Aosaki

Studio
Lapin Track

Undead Murder Farce pretty much does what it says in the title, as it’s a farce featuring a wild mix of horror, action-adventure, and 19th-century novel characters rather than a grounded drama. Sherlock Holmes and Moriarty turn up, as does Phileas Fogg from Around the World in 80 Days, the Phantom from The Phantom of the Opera, and real notorious figures from history like Jack the Ripper and Aleister Crowley.

But the main heroes of the story are a duo wronged by a mysterious villain known only as M. They decapitated the immortal yōkai Aya, reducing her to a talking head. Then they injected oni blood into the oni hunter Tsugaru, which gave him extra strength but doomed him to eventually fully becoming a demon. With Aya’s maid Shizuku in tow, the two head to Europe to find M, get Aya’s body back and get revenge.

3 House of Five Leaves

MyAnimeList Score: 7.77

Akitsu Masanosuke in House Of Five Leaves

  • Creator: Natsume Ono.
  • Studio: Manglobe.
  • 1 Season, 12 Episodes.
  • Available on Viewster, Retro Crush, and Cineverse.

All these adventures in Europe are fine enough, but if fans are after something closer to TAD, they may prefer something closer geographically too. House of Five Leaves heads back East but goes a little too far past China and into feudal Japan, where the ronin samurai Akitsu seeks work. He’s fantastic with a sword, though his timid personality doesn’t make him particularly desirable to employers.

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He gets a breakthrough when a man called Yaichi hires him as a bodyguard for his group of bandits, the Five Leaves. At first, Akitsu is unaware of their illegal activities, but once he finds out, he’s split between leaving them on moral grounds or staying to earn some decent cash. He eventually stays as, aside from the money, there’s a mystery behind Yaichi and his past that he wants to figure out.

2 Raven of the Inner Palace

MyAnimeList Score: 7.52

Anime Like The Apothecary Diaries- Raven of the Inner Palace

  • Creator: Kōko Shirakawa.
  • Studio: Bandai-Namco Pictures.
  • 1 Season, 13 Episodes.
  • Available on Crunchyroll.

Heading back across the sea, Raven of the Inner Palace uses a Chinese setting like TAD but is set in more ancient times. It still features a woman who works in the Royal Court to cure people. The difference is that Liu Shouxue is the successor to the ‘Raven’ Consort’ title, and she treats them after they’ve died by summoning their spirits and exorcising/purifying them in order to help them move on peacefully. Yet her work intimidates her colleagues.

To them, she’s either some immortal sage or a revenant ready to curse anyone who wrongs her. In truth, she was a member of the old Luan dynasty who was adopted by the prior Raven Consort and must dye her naturally silver hair black to keep her identity secret. If anyone else finds out the truth, she’ll be executed as a threat to the state. As handy as she is to the court, she knows her fate always hangs in the balance.

1 The Story of Saiunkoku

MyAnimeList Score: 7.89

Anime Like The Apothecary Diaries- The Story of Saiunkoku

The Story of Saiunkoku
Seasons
2

Number of Episodes
78

Streaming Service(s)
Tubi

Studio
Madhouse

Raven of the Inner Palace also has a romantic subplot where its Emperor has feelings for Liu and tries to help her keep her disguise, but Liu must stay single to serve as the Raven Consort. It’s a good choice for people who like darker tales, while those who prefer something a little lighter may prefer The Story of Saiunkoku.

Shūrei is part of a fallen noble family who dreams of serving a civil position in the Chinese-inspired fictional nation of Saiunkoku. However, government posts are forbidden to women. But then she gets an offer where she’ll be paid 500 gold coins if she successfully teaches the new emperor how to rule responsibly. She readily accepts as she finally gets to be part of the royal court, only to discover there’s more to the job and to the emperor than she thought.

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